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Андрология и генитальная хирургия

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Анеуплодия в сперматозоидах у фертильных мужчин и пациентов с нарушением репродукции

https://doi.org/10.17650/1726-9784-2021-22-4-27-35

Полный текст:

Аннотация

В статье рассматриваются современные данные по анеуплоидии в сперматозоидах у здоровых (фертильных) мужчин и пациентов с нарушением репродуктивной функции. Обсуждаются механизмы возникновения анеуплоидии в половых клетках и факторы, влияющие на ее уровень, связь с аномалиями кариотипа, нарушениями сперматогенеза, мейоза и снижением показателей сперматозоидов, а также влияние анеуплоидии в мужских гаметах на фертильность мужчин, развитие эмбриона и вынашивание беременности.

Об авторах

А. О. Седова
Медико-генетический научный центр им. акад. Н.П. Бочкова
Россия

115522 Москва, ул. Москворечье, 1.



А. И. Мартемьянова
Медико-генетический научный центр им. акад. Н.П. Бочкова
Россия

115522 Москва, ул. Москворечье, 1.



В. Б. Черных
Медико-генетический научный центр им. акад. Н.П. Бочкова
Россия

Черных Вячеслав Борисович.

115522 Москва, ул. Москворечье, 1.



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Рецензия

Для цитирования:


Седова А.О., Мартемьянова А.И., Черных В.Б. Анеуплодия в сперматозоидах у фертильных мужчин и пациентов с нарушением репродукции. Андрология и генитальная хирургия. 2021;22(4):27-35. https://doi.org/10.17650/1726-9784-2021-22-4-27-35

For citation:


Sedova A.O., Martemyanova A.I., Chernykh V.B. Aneuploidy in sperm of fertile men and patients with impaired fertility. Andrology and Genital Surgery. 2021;22(4):27-35. (In Russ.) https://doi.org/10.17650/1726-9784-2021-22-4-27-35

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ISSN 2070-9781 (Print)
ISSN 2412-8902 (Online)

 

 

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