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Андрология и генитальная хирургия

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Вирусное инфицирование сперматозоидов. Часть 1. Вирус гепатита В, вирус папилломы человека (обзор литературы)

https://doi.org/10.17650/2070-9781-2020-21-4-12-19

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Аннотация

Интрагаметное вирусное инфицирование сперматозоидов может быть причиной истинной вертикальной передачи вирусов через половые клетки. В настоящее время в сперматозоидах обнаружены вирус папилломы человека (в том числе штаммы онкогенного риска), вирус гепатита В. Доказана возможность вертикальной передачи этих вирусов.

Интрагаметное инфицирование сперматозоидов вирусом папилломы человека и вирусом гепатита В приводит к аномалиям развития эмбриона и может стать причиной спонтанного аборта как после естественного зачатия, так и после зачатия с применением вспомогательных репродуктивных технологий.

Разработка адекватных методов диагностики интрагаметного вирусного инфицирования сперматозоидов позволит в некоторых случаях установить причину бесплодия и аномалий развития эмбриона и назначить необходимую антивирусную терапию на стадии подготовки к естественному зачатию или к применению вспомогательных репродуктивных технологий.

Об авторе

Е. Е. Брагина
Научно-исследовательский институт физико-химической биологии им. А. Н. Белозерского ФГБОУ ВО «Московский государственный университет им. М. В. Ломоносова»; ФГБНУ «Медико-генетический научный центр им. Н. П. Бочкова»
Россия

Елизавета Ефимовна Брагина

119992 Москва, Ленинские горы, 1, стр. 40

115522 Москва, ул. Москворечье, 1



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Для цитирования:


Брагина Е.Е. Вирусное инфицирование сперматозоидов. Часть 1. Вирус гепатита В, вирус папилломы человека (обзор литературы). Андрология и генитальная хирургия. 2020;21(4):12-19. https://doi.org/10.17650/2070-9781-2020-21-4-12-19

For citation:


Bragina E.E. Viral infection of spermatozoa. Part 1. Hepatitis B virus and human papillomavirus (review). Andrology and Genital Surgery. 2020;21(4):12-19. (In Russ.) https://doi.org/10.17650/2070-9781-2020-21-4-12-19

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ISSN 2070-9781 (Print)
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