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Андрология и генитальная хирургия

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Механизм движения жгутиков сперматозоидов

https://doi.org/10.17650/2070-9781-2018-19-3-15-26

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Аннотация

Механизм движения ресничек и жгутиков сперматозоидов основан на скольжении дуплетов микротрубочек друг относительно друга благодаря поступательному движению динеинов – моторных белков, способных перемещаться по поверхности микротрубочек и трансформирующих химическую энергию, содержащуюся в аденозинтрифосфате, в механическую энергию движения. Ранее внешние и внутренние динеиновые ручки считали сходными по структуре и функциям, однако недавно полученные экспериментальные данные свидетельствуют о значительном их различии по составу субъединиц, расположению в аксонеме и механизмам регуляции. И хотя понимание принципов изменения активности описанных моторных белков остается неполным, установлены тонкие механизмы функционирования данных структур.

Об авторах

С. А. Руднева
ФГБНУ Медико-генетический научный центр
Россия

Светлана Айвенговна Руднева

115522 Москва, ул. Москворечье, 1



В. Б. Черных
ФГБНУ Медико-генетический научный центр
Россия

115522 Москва, ул. Москворечье, 1



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Для цитирования:


Руднева С.А., Черных В.Б. Механизм движения жгутиков сперматозоидов. Андрология и генитальная хирургия. 2018;19(3):15-26. https://doi.org/10.17650/2070-9781-2018-19-3-15-26

For citation:


Rudneva S.A., Сhernykh V.B. A mechanism of sperm cilia beating. Andrology and Genital Surgery. 2018;19(3):15-26. (In Russ.) https://doi.org/10.17650/2070-9781-2018-19-3-15-26

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